ELISA DNASE1 anti-

Quantity :50µL Clone Number: Aliases:Deoxyribonuclease 1 antibody; Deoxyribonuclease I antibody; Deoxyribonuclease-1 antibody; Deoxyribonuclease1 antibody; DeoxyribonucleaseI antibody; DNAS1_ antibody; DNASE 1 antibody; DNase I antibody; DNase I lysosomal antibody; DNASE1 antibody; DNaseI antibody; DNL 1 antibody; DNL1 antibody; Dornase alfa antibody; DRNI antibody; FLJ38093 antibody; urine deoxyribonuclease I antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P24855 Immunogen:Fusion protein of DNASE1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:This gene encodes a member of the DNase family. This protein is stored in the zymogen granµLes of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 throµgh DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellµLar DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroµghly characterized. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNASE1 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism