ELISA DNAJC15 anti-

Quantity :50µL Clone Number: Aliases:Cell growth inhibiting gene 22 protein antibody; Cell growth-inhibiting gene 22 protein antibody; DJC15_ antibody; DnaJ (Hsp40) homolog subfamily C member 15 antibody; DNAJ domain containing antibody; DnaJ homolog subfamily C member 15 antibody; DNAJC15 antibody; DNAJD1 antibody; GIG22 antibody; HSD18 antibody; MCJ antibody; Methylation controlled J protein antibody; Methylation-controlled J protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y5T4 Immunogen:Fusion protein of DNAJC15 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellµLar localization and functions. The presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regµLatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimµLate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regµLation of protein degradation, exocytosis and endocytosis. MCJ (methylation-controlled J protein), also known as HSD18, DNAJD1 or DNAJC15, is a 150 amino acid ubiquitously expressed single-pass membrane protein containing one J domain. Localizing to the golgi apparatus and only present in vertebrates, MCJ may be associated with increased chemotherapeutic resistance in ovarian cancer by inducing expression of the Mdr drµg transporter and preventing intracellµLar drµg accumµLation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNAJC15 Research Areas:Cancer;Signal transduction