ELISA DKK3 anti-

Quantity :100µL Clone Number: Aliases:Dickkopf 3 antibody; Dickkopf 3 homolog (Xenopus laevis) antibody; Dickkopf 3 homolog antibody; Dickkopf homolog 3 antibody; Dickkopf related protein 3 antibody; Dickkopf related protein 3 Precursor antibody; Dickkopf WNT signaling pathway inhibitor 3 antibody; Dickkopf; Xenopus; homolog of; 3 antibody; Dickkopf-3 antibody; Dickkopf-related protein 3 antibody; Dickkopf3 antibody; DKK 3 antibody; Dkk-3 antibody; DKK3 antibody; DKK3_ antibody; hDkk 3 antibody; hDkk-3 antibody; hDkk3 antibody; RegµLated in glioma antibody; REIC antibody; RIG antibody; RIG-like 5-6 antibody; RIG-like 7-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UBP4 Immunogen:SyntheQuantityd peptide derived from internal of DKK3. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regµLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adµLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease By similarity. Shimizu K., Gene 282:151-158(2002). Gray A.M., Genome Res. 13:2265-2270(2003). Niehrs C., Oncogene 25:7469-7481(2006). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DKK3 Research Areas:Signal transduction?Stem cells